D-R9/GT Peptide/Peptide Mea Hoʻolako

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D-R9he peptide lāʻau lapaʻau, ʻo ka hiʻohiʻona he pauka keʻokeʻo, ʻo ka peptide he synthesis kemika artificial, no ka noiʻi ʻepekema wale nō, ʻaʻole no ka hoʻohana kanaka.Aia nā kūlana mālama mai ka 80 maikaʻi ʻole° C i ka 20 maikaʻi ʻole° C.

Nā kikoʻī

ʻAno: Keʻokeʻo a keʻokeʻo pauka

Maʻemaʻe (HPLC):≥98.0%

Hoʻokahi haumia:≤2.0%

Maʻiʻo Acetate (HPLC): 5.0%～12.0%

Waiwai (Karl Fischer):≤10.0%

Maʻiʻo Peptide:≥80.0%

Hoʻopili a me ka hoʻouna ʻana: Haʻahaʻa haʻahaʻa, hoʻopaʻa haʻahaʻa, pololei i ka mg e like me ka makemake.

Pehea e kauoha ai?

1. Contact us directly by phone or email: +86-13735575465, sales1@gotopbio.com.

2. E kauoha ma ka pūnaewele.E ʻoluʻolu e hoʻopiha i ka palapala kauoha ma ka pūnaewele.

3. Hāʻawi i ka inoa peptide, CAS No. a i ʻole ke kaʻina, ka maʻemaʻe a me ka hoʻololi inā makemake ʻia, ka nui, a me nā mea ʻē aʻe e hāʻawi mākou i kahi ʻōlelo i loko o 2 mau hola.

4. E kauoha i ka conformation e ka aelike kuai i kakau pono ia a me ka NDA (non disclosure agreement) a i 'ole ka aelike huna.

5. E hoʻomau mau mākou i ka holomua o ke kauoha i ka manawa.

6. Hāʻawi ʻia ka peptide e DHL, Fedex a i ʻole nā ​​​​mea ʻē aʻe, a me HPLC, MS, COA me ka ukana.

7. E hahai ʻia ke kulekele hoʻihoʻi inā he ʻokoʻa o kā mākou maikaʻi a lawelawe paha.

8. ʻO ka lawelawe ma hope o ke kūʻai aku: Inā he nīnau kā mākou mea kūʻai e pili ana i kā mākou peptide i ka wā o ka hoʻokolohua, e ʻoluʻolu e kelepona iā mākou a e pane mākou iā ia i ka manawa pōkole.

Hoʻohana wale ʻia nā huahana a pau o ka hui no ka noiʻi ʻepekema, ʻo ia's pāpā ʻia e hoʻohana pololei ʻia e kekahi kanaka ma ke kino kanaka.

FAQ：

Ua hōʻemi ʻia nā peptides i loaʻa iā Cys ma mua o ka hoʻouna ʻana?

Inā ʻaʻole ʻike ʻia ka peptide i hoʻokahe ʻia, ʻaʻole mākou e hōʻemi i ka Cys.Loaʻa nā polypeptides a pau mai nā huahana crude i hoʻomaʻemaʻe ʻia a lyophilized ma lalo o nā kūlana pH2, ka mea ma kahi liʻiliʻi e pale i ka oxidation o Cys.Hoʻomaʻemaʻe ʻia nā peptides i loaʻa iā Cys ma ka pH2 ke ʻole he kumu kikoʻī e hoʻomaʻemaʻe ai i ka pH6.8.Inā hana ʻia ka hoʻomaʻemaʻe ʻana ma ka pH6.8, pono e mālama koke ʻia ka huahana i hoʻomaʻemaʻe ʻia me ka waikawa i mea e pale ai i ka oxidation.Ma ka ʻanuʻu hoʻomalu maikaʻi hope loa, no nā peptides i loaʻa iā Cys, inā ʻike ʻia ka nui o ke kaumaha molekala (2P+H) ma ka palapala ʻāina MS, hōʻike ia ua hana ʻia kahi dimer.Inā ʻaʻohe pilikia me MS a me HPLC, e lyophilize pololei mākou a hoʻouna i nā waiwai me ka ʻole o ka hana hou ʻana.Pono e hoʻomaopopo ʻia ʻo nā peptides e loaʻa ana iā Cys e hoʻoheheʻe lohi i ka manawa, a ʻo ke kiʻekiʻe o ka oxidation e pili ana i ke kaʻina peptide a me nā kūlana mālama.

Pehea ʻoe e hoʻoholo ai inā pili ʻia kahi peptide?

Hoʻohana mākou i ka pane ʻo Ellman e hoʻāʻo ai inā ua pau ke apo.Inā maika'i ka ho'ā'o 'Ellman (melemele), 'a'ole i piha ka pane apo.Inā maikaʻi ʻole nā ​​hopena hoʻāʻo (ʻaʻole melemele), ua pau ka pane apo.ʻAʻole mākou e hāʻawi i ka hōʻike loiloi o ka ʻike cyclization no kā mākou mea kūʻai.ʻO ka mea maʻamau, aia ka wehewehe ʻana i nā hopena hoʻāʻo a Ellman ma ka hōʻike QC.

Pono wau i kahi peptide cyclic, aia kahi tryptophan, e hoʻoheheʻe ʻia?

ʻO ka oxidation o tryptophan he mea maʻamau i ka peptide oxidation, a ʻo ka peptides ka mea maʻamau ma mua o ka hoʻomaʻemaʻe ʻana.Inā hiki mai ka ho'ohāhā o tryptophan, e ho'ololi ka manawa pa'a o ka peptide ma ke kolamu HPLC, a hiki ke ho'opau 'ia ka oxidation e ka ho'oma'ema'e.Eia kekahi, hiki ke ʻike ʻia nā peptides oxidized e MS.

Pono anei e kau i kahi āpau ma waena o ka peptide a me ka wai?

Inā ʻoe e hoʻopili i kahi mole nui (e like me ka dye) i ka peptide, ʻoi aku ka maikaʻi o ka waiho ʻana i kahi ākea ma waena o ka peptide a me ka ligand e hōʻemi i ka hoʻopilikia ʻana i ka mea loaʻa ma o ka pelu ʻana o ka peptide ponoʻī a i ʻole ka pelu ʻana o ka peptide. kona conjugate.ʻAʻole makemake nā poʻe ʻē aʻe i nā wā āpau.No ka laʻana, i ka pelu ʻia ʻana o nā protein, hiki ke hoʻoholo i ka mamao o ke kaʻawale ʻana o ka hoʻopili ʻana o kahi waikawa amino ma o ka hoʻopili ʻana i kahi dye fluorescent i kahi kahua.

Inā makemake ʻoe e hana i kahi hoʻololi biotin ma ka pahu N, pono ʻoe e kau i kahi āpau ma waena o ka biotin a me ke kaʻina peptide?

ʻO ke kaʻina hana lepili biotin maʻamau i hoʻohana ʻia e kā mākou hui e hoʻopili i kahi Ahx i ke kaulahao peptide, a ukali ʻia e biotin.ʻO Ahx kahi pūhui 6-carbon e hana i ka pale ma waena o ka peptide a me ka biotin.

Hiki iā ʻoe ke hāʻawi i kekahi ʻōlelo aʻo e pili ana i ka hoʻolālā ʻana o nā peptides phosphorylated?

I ka piʻi ʻana o ka lōʻihi, e emi mālie ana ka hana hoʻopaʻa ʻana mai ka waikawa amino phosphorylated ma luna.ʻO ke kuhikuhi synthesis mai ka C terminal a i ka N terminal.Manaʻo ʻia nā koena ma hope o ka phosphorylated amino acid ʻaʻole i ʻoi aku ma mua o 10, ʻo ia hoʻi, ʻo ka nui o nā koena amino acid ma mua o ka phosphorylated amino acid mai ka N terminal a i ka C terminal ʻaʻole pono ma mua o 10.

No ke aha ka n-terminal acetylation a me C-terminal amidation?

Ke pale nei kēia mau hoʻololi i ka peptide mai ka hoʻohaʻahaʻa ʻia a ʻae i ka peptide e hoʻohālike i kona kūlana mua o nā alpha amino a me nā hui carboxyl i loko o ka protein makua.