He hoʻolauna pōkole i ka tidulutide

ʻO ka hana o ka tidulutide Gattex (teduglutide)

ʻO Teduglutide kahi mea hoʻohālikelike kūlohelohe kanaka o glucagon-like peptide-2 (GLP-2), kahi peptide i huna ʻia e nā pū L i loko o ka ʻōpū distal.Ua ʻike ʻia ʻo GLP-2 e hoʻomaikaʻi i ke kahe o ke koko a me ka portal a pale i ka huna ʻana o ka ʻōpū o ka ʻōpū.No nā degere o ka lu peptide a me ka peptide receptor 2 glucagon laʻana, insulin-like ulu kumu i loko o ka intestinal endocrine cell, epithelial cell of muscle fiber, submucosa and myenteric stands between intestinal neurons.ʻO ka hoʻāla ʻia ʻana o kēia mau mea loaʻa ke kumu o ka hoʻokuʻu ʻia ʻana o nā ʻano media like ʻole, me ka insulin-like growth factor (IGF) 1, cell growth factor formation nitrogen oxide a me ka cutin cell growth factor (KGF).

ʻO Tidulutide, kahi glucagon-like peptide 2 (GLP-2) analogue, e hōʻemi ana i ka hoʻokaʻawale ʻana o ka ʻōpū a me ka metabolism a hoʻoponopono i ka ulu ʻana, hana hou a me ka hoʻihoʻi ʻana o nā ʻāpana lining intestinal.Hoʻonui ka Peptide i ka helu o kēia mau pūnaewele, hiki ke hoʻonui i ka absorption o ka ʻōpū liʻiliʻi, hoʻemi i ka maʻi maʻi.Hiki ke mālama ʻia ka maʻi ʻōpū pōkole i nā pākeke.Ua lilo ka lāʻau lapaʻau i mau lāʻau lapaʻau mua i manaʻo ʻia i kahi mea kakaʻikahi akā nāwaliwali loa.

He hoʻolauna pōkole i ka tidulutide

ʻO ke ʻano molekiko kemika o tidulutide

Nā palena kumu

Inoa: no c peptide (Teduglutide)

Helu: GT – F027

Helu CAS: 197922-42-2

Sequence: His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn- Trp-Leu-Ile-Gln-Thr-Lys- Ile-Thr-Asp

Huina mole: C164H252N44O55S

Kaumaha molekula: 3752.08248