Ma kēia pepa, ua hoʻokomo ʻia ʻelua mau ʻakika amino kumu, ʻo glycine (Gly) a me alanine (Ala).ʻO ka mea nui kēia no ka mea hiki iā lākou ke hana ma ke ʻano he amino acid a me ka hoʻohui ʻana i nā hui iā lākou e hiki ke hana i nā ʻano amino acids ʻē aʻe.
He ʻono koʻikoʻi ko Glycine, no laila ua loaʻa mai kona inoa Pelekane mai ka Greek glykys(sweet).ʻO ka unuhi Kina o glycine ʻaʻole wale ka manaʻo o ka "ʻono", akā loaʻa pū kekahi i ka ʻōlelo like, hiki ke kapa ʻia ʻo ke kumu hoʻohālike o ka "ʻoiaʻiʻo, hoʻokō a me ka nani".Ma muli o kona ʻono ʻono, hoʻohana pinepine ʻia ka glycine ma ke ʻano he mea ʻono i ka ʻoihana meaʻai e wehe i ka ʻawaʻawa a hoʻonui i ka ʻono.He liʻiliʻi ke kaulahao ʻaoʻao o ka glycine me hoʻokahi wale nō hydrogen atom.ʻOkoʻa kēlā iā ia.He ʻakika amino kumu me ka ʻole o ka chirality.
Hōʻike ʻia ʻo Glycine i loko o nā protein e kona liʻiliʻi liʻiliʻi a me ka maʻalahi.No ka laʻana, ʻo ka hoʻohālikelike helix ʻekolu o ka collagen he mea kūikawā loa.Pono e loaʻa i hoʻokahi glycine no kēlā me kēia koena ʻelua, inā ʻaʻole e hoʻonui nui ʻia ka steric hindrance.Pēlā nō, ʻo ka pilina ma waena o nā kāʻei kapu ʻelua o kahi protein e koi pinepine i ka glycine e hāʻawi i ka loli conformational.Eia naʻe, inā maʻalahi ka glycine, ʻaʻole lawa kona kūpaʻa.
ʻO Glycine kekahi o nā mea hao i ka wā o ka hoʻokumu ʻana o α-helix.ʻO ke kumu he liʻiliʻi loa nā kaulahao ʻaoʻao e hoʻopaʻa i ka conformation i nā mea āpau.Eia kekahi, hoʻohana pinepine ʻia ka glycine e hoʻomākaukau ai i nā hoʻonā buffer.ʻO ka poʻe o ʻoukou e hana electrophoresis e hoʻomanaʻo pinepine i kēlā.
No ka German acetaldehyde ka inoa Pelekane o ka alanine, a ua maʻalahi ka hoʻomaopopo ʻana i ka inoa Kina no ka mea he ʻekolu kalapona ka alanine a ʻo kona inoa kemika he alanine.He inoa maʻalahi kēia, e like me ke ʻano o ka amino acid.ʻO ke kaulahao ʻaoʻao o ka alanine hoʻokahi wale nō hui methyl a ʻoi aku ka nui ma mua o ka glycine.I koʻu kaha kiʻi ʻana i nā kumu hoʻohālike no nā ʻakika amino ʻē aʻe he 18, ua hoʻohui au i nā hui i ka alanine.I loko o nā protein, ua like ka alanine me ka pōhaku lepo, kahi mea hale maʻamau i kūʻē ʻole me kekahi.
ʻO ke kaulahao ʻaoʻao o ka alanine he ʻuʻuku liʻiliʻi a aia ma ka α-helix, ʻo ia ka conformation.Paʻa loa nō hoʻi i ka β-pele ʻia.I ka ʻenekinia protein, inā makemake ʻoe e hoʻololi i kahi amino acid me ka ʻole o ka pahuhopu kikoʻī i kahi protein, hiki iā ʻoe ke hoʻololi iā ia i ka alanine, ʻaʻole maʻalahi ke luku i ka conformation holoʻokoʻa o ka protein.
Ka manawa hoʻouna: Mei-29-2023