E pili ana iā mākou:
ʻO ka peptide kahi kaulahao o nā waikawa amino i hoʻopili ʻia e nā paʻa peptide.Hoʻokomo nui nā peptides i ka hoʻoponopono protein, angiogenesis, ka hoʻonui ʻana o ka cell, melanogenesis, ka neʻe ʻana o ka cell, a me ka mumū.Ua hoʻohana nui ʻia nā peptides bioactive i ka ʻoihana cosmetic i nā makahiki i hala iho nei.Pono nā peptide i ke kaumaha molekala haʻahaʻa (> 500 Da), i mea e hōʻemi ai i ka diffusion o ka peptide ma waena o nā papa epidermal, ke kūpaʻa kiʻekiʻe a me ka solubility.I loko o nā makahiki, ua hoʻomohala ke kaiāulu ʻepekema i kahi ʻāpana peptide synthetic liʻiliʻi a paʻa e hoʻāla ai i ka hana collagen a hōʻemi i nā wrinkles maka a me ka pigmentation.Trifluoroacetyl tripeptide-2 (sequence: TFA-Val-Try-Val-OH) tripeptide synthesis, i hoʻolālā ʻia e like me ka matrix metalloproteinase a me ka elastase inhibitor.ʻO nā haʻawina in vitro e pili ana i ka pale ʻana o ECM e trifluoro-acetyl tripeptide 2(TT2), ka synthesis o ka proteoglycan i loko o nā pilina cell-matrix, a me ka hopena i ka synthesis progerin i nā fibroblasts maʻamau kanaka makua ua ʻike hou ʻia he co-inducer o cellular. ʻelemakule.Hōʻike nā hopena i ka trifluoroacetyl tripeptide 2 i kahi ākea ākea o nā waiwai anti-aging.Hoʻemi kēia i ka synthesis progerin, hoʻonui i ka hana proteoglycan, a hōʻemi i ka collagen, a laila e hōʻemi ana i nā wrinkles a hoʻomaikaʻi i ka ʻoʻoleʻa.Eia kekahi, ua loiloi ʻia kāna mau anti-wrinkling, anti-flow hanging a me ka hoʻopaʻa ʻana i ka ʻili i nā haʻawina ʻelua in vitro split face.Ua hōʻike ʻia ʻo Trifluoroacetyl tripeptide 2 i nā hopena holomua i nā wrinkles, paʻa, elasticity, a me ka sagging.
Hiki i ka trifluoroacetyl tripeptide-2 ke hoʻopaneʻe i ka ʻelemakule?
Ua hōʻike nā haʻawina e pili pono ana ka senescence cell me Progerin.Me ka ʻelemakule, ʻoi aku ka nui o ka presenilin i loko o ke kino, e alakaʻi ana i nā hemahema nuklea a me ka pōʻino DNA, e alakaʻi ana i kahi ʻano o ka ʻeleʻele o ka ʻili.ʻO Trifluoroacetyl tripeptide-2 kahi tripeptide ikaika o Elafin, kahi derivative o ka elastase inhibitor.Hoʻemi ia i ka synthesis Progerin a hoʻomaikaʻi i ka laxity o ka ʻili, sagging a me nā wrinkles.
Mechanism
1. Kāohi i ka synthesis o Progerin no ka hoʻopaneʻe ʻana i ke ʻano o ke kelepona.
2. Hoʻoikaika i ka hana syndecan a hoʻolōʻihi i ke ola o ke kelepona.
3. Kāohi i ka hana o ka matrix metalloproteinases MMP1, MMP3 a me MMP9, e hoʻemi i ka haki ʻana o nā protein matrix extracellular a mālama i ko lākou kūpaʻa.
4. Kāohi i ka hana elastase, hoʻemi i ka hoʻohaʻahaʻa ʻana i ka elastin, a ʻoi aku ka paʻa o ka ʻili.
Palapala noi
He kūpono ia no nā ʻano anti-wrinkle a me ka anti-aging, hoʻoponopono paʻa, anti-photoaging, post-natal a post-sun mālama kino, etc. Ua hoʻohui ʻia i ka pae hope o ka hana hoʻonaninani
Ka manawa hoʻouna: Mei-22-2023