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OctreotideʻO ka acetate kahi hana lōʻihi o ka somatostatin synthetic analogue a ʻoi aku ka ikaika o ka ulu ʻana o ka hormone ulu, glucagon a me ka insulin ma mua o ka somatostatin.ʻO ka maʻi, hoʻohana nui ʻia ka octreotide e mālama i ka esophageal variceal bleeding i hoʻokumu ʻia e ka hypertension portal, acromegaly, gastrointestinal bleeding e like me cirrhosis, esophageal variceal bleeding, Chemicalbook peptic ulcer bleeding and stress ulcer bleeding, pancreatic maʻi e like me ka maʻi pancreatic koʻikoʻi, ʻeha pancreatic a postoperative paha. fistula, a no ka pale ʻana i nā pilikia ma hope o ka ʻoki ʻana i ka pancreatic.
Nā kikoʻī
ʻAno: Keʻokeʻo a keʻokeʻo pauka
Maʻemaʻe (HPLC):≥98.0%
Hoʻokahi haumia:≤2.0%
Maʻiʻo Acetate (HPLC): 5.0%~12.0%
Waiwai (Karl Fischer):≤10.0%
Maʻiʻo Peptide:≥80.0%
Hoʻopili a me ka hoʻouna ʻana: Haʻahaʻa haʻahaʻa, hoʻopaʻa haʻahaʻa, pololei i ka mg e like me ka makemake.
Pehea e kauoha ai?
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2. E kauoha ma ka pūnaewele.E ʻoluʻolu e hoʻopiha i ka palapala kauoha ma ka pūnaewele.
3. Hāʻawi i ka inoa peptide, CAS No. a i ʻole ke kaʻina, ka maʻemaʻe a me ka hoʻololi inā makemake ʻia, ka nui, a me nā mea ʻē aʻe e hāʻawi mākou i kahi ʻōlelo i loko o 2 mau hola.
4. E kauoha i ka conformation e ka aelike kuai i kakau pono ia a me ka NDA (non disclosure agreement) a i 'ole ka aelike huna.
5. E hoʻomau mau mākou i ka holomua o ke kauoha i ka manawa.
6. Hāʻawi ʻia ka peptide e DHL, Fedex a i ʻole nā mea ʻē aʻe, a me HPLC, MS, COA me ka ukana.
7. E hahai ʻia ke kulekele hoʻihoʻi inā he ʻokoʻa o kā mākou maikaʻi a lawelawe paha.
8. ʻO ka lawelawe ma hope o ke kūʻai aku: Inā he nīnau kā mākou mea kūʻai e pili ana i kā mākou peptide i ka wā o ka hoʻokolohua, e ʻoluʻolu e kelepona iā mākou a e pane mākou iā ia i ka manawa pōkole.
Hoʻohana wale ʻia nā huahana a pau o ka hui no ka noiʻi ʻepekema, ʻo ia's pāpā ʻia e hoʻohana pololei ʻia e kekahi kanaka ma ke kino kanaka.
FAQ:
ʻO wai ka hopena maikaʻi loa no kaʻu noiʻi?
Ma ka maʻamau, hoʻopau ka peptide me kahi hui amino manuahi N-terminal a me kahi hui carboxyl manuahi C-terminal.Hōʻike pinepine ka peptide sequence i ke kaʻina o ka protein makuahine.I mea e pili kokoke ai i ka protein makuahine, pono e pani pinepine ka hopena o ka peptide, ʻo ia hoʻi, n-terminal acetylation a me C-terminal amidation.Ke pale nei kēia hoʻololi i ka hoʻokomo ʻana i ka uku keu, a ʻoi aku ka hiki ke pale i ka hana exonucliase, i ʻoi aku ka paʻa o ka peptide.
ʻO wai nā polypeptides i hoʻololi ʻia i hiki ke synthesized i ka peptide Kina?
Hāʻawi kā mākou hui i nā ʻano lepili peptide i hoʻololi ʻia, e like me ka acetylation, biotin labeling, phosphorylation modification, fluorescence modification, hiki ke hana ʻia e like me kāu mau pono kūikawā.
Pehea ʻoe e hoʻopau ai i nā polypeptides?
ʻO ka solubility o ka polypeptide e hilinaʻi nui ʻia i kona ʻano kumu mua a me ke kula kiʻekiʻe, ke ʻano o ka lepili hoʻololi, ke ʻano solvent a me ka ʻike hope.Inā hiki ʻole ke hoʻoheheʻe ʻia ka peptide i ka wai, hiki i ke ultrasound ke kōkua i ka hoʻopau ʻana.No ka peptide kumu, ua ʻōlelo ʻia e hoʻoheheʻe me 10% acetic acid;No nā peptides acidic, hoʻopau ʻia me 10%NH4HCO3.Hiki ke hoʻohui ʻia nā solvents organik i nā polypeptides insoluble.Hoʻoheheʻe ʻia ka peptide i ka liʻiliʻi liʻiliʻi o ka solvent organik (eg, DMSO, DMF, isopropyl alcohol, methanol, etc.).Manaʻo nui ʻia e hoʻoheheʻe ʻia ka peptide i loko o ka mea hoʻoheheʻe organik ma mua a laila hoʻohui mālie ʻia i ka wai a i ʻole ka mea pale ʻē aʻe a hiki i ka manaʻo i makemake ʻia.
He aha nā kūlana mālama maikaʻi loa?Pehea ka paʻa o ka peptide?
Ma hope o ka lyophilized, hiki i ka polypeptide ke hana i ka fluff a i ʻole flocculant pauka, hiki ke pale i ka hōʻino mua ʻana o ka polypeptide.Manaʻo ʻia no ka mālama ʻana: a.-20℃mālama a maloʻo paha b.E ho'āʻo e hōʻalo i ka hoʻoheheʻe hou ʻana c.E ho'āʻo e pale i ka waiho ʻana ma ke kūlana hoʻonā (hiki ke mālama ʻia ka pauda maloʻo maloʻo i loko o nā pūʻolo kaʻawale no ka maʻalahi o ka hoʻohana ʻana) d.Inā pono e mālama ʻia i loko o ka hopena, ʻōlelo ʻia e hoʻopau i nā peptides i ka wai sterile ma lalo o nā kūlana acidic nāwaliwali a mālama i ka -20℃.
Pehea ka lawe ʻia ʻana o kaʻu peptide?He aha nā hōʻike hoʻāʻo i hāʻawi ʻia?
Hoʻopaʻa mau ʻia nā polypeptides maloʻo maloʻo a pau i loko o nā pahu kūikawā o 2 ml a i ʻole 10ml me ka ʻikepili analytical kumu a me nā hōʻike synthesis i loaʻa nā ʻike koʻikoʻi e like me ke kaʻina, ke kaumaha molekala, ka maʻemaʻe, ke kaumaha, a me ka helu o ka polypeptide.
He aha ke kaumaha ʻupena?He aha ka peptide content?
Ma hope o ka lyophilized peptide e like me ka fluffy a me ka fluff-like, hiki ke loaʻa ka nui o ka wai, adsorbed solvents a me nā paʻakai ma muli o nā ʻano o ka peptide ponoʻī.ʻAʻole kēia manaʻo ʻaʻole lawa ka maʻemaʻe o ka peptide, akā ua hoʻemi ʻia ka ʻike maoli o ka peptide e 10% a 30%.ʻO ke kaumaha nui o ka peptide ke kaumaha maoli o ka peptide me ka wai a me nā ion protonated.I mea e hōʻoia ai i ka neʻe ʻana o ka peptide, pono e wehe ʻia nā mea non-peptide mai ka peptide crude.
Pehea ka maʻemaʻe o ka peptide?
Hiki i kā mākou hui ke hāʻawi i nā pae hoʻomaʻemaʻe like ʻole no nā mea kūʻai aku e koho mai, mai ka crude a i> 99.9% maʻemaʻe.Wahi a nā mea kūʻai aku hiki iā mākou ke hāʻawi i ka maʻemaʻe> 99.9% ultra-pure polypeptide.